Melanistic mask EM (black mask)

In connection with the melanistic mask, the allele E^Mhas been identified that was created by point-substitution c.799A

However, not all dogs with the E^M-allele have a melanistic mask. With dogs having brown, black or blue coat, it is often difficult to distinguish the melanistic mask from the coat colour.

Examples:

• Brindle greyhound with dilution gene (D-locus) - the light-grey brindling turns in fawn brindling - the melanistic mask may merge with the overall coat colour (the black mask turns grey or even white)
• Scottish Deerhound breed is usually grey-spotted and the melanistic mask may merge with the overall coat colour (the black mask turns grey or even white)

The colour of the melanistic mask corresponds with the other genes affecting the production of the eumelanin type and therefore, the melanistic mask may not be always black.

The E^M-locus test is suitable in particular for the following breeds: Afghan, Bull Mastif, Cairn Terrier, Cardigan Welsh Corgi, German Shepherd, Great Dane, Greyhound, Saluki, Staffordshire Bull Terrier, Whippet.

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Information about ordering the locus tests

The prices of the individual locus tests are stated in the price list. To each order of coat colour test for one dog, an extra fee amounting to 16.70 EUR incl. VAT will be charged for preparation of the sample and DNA-isolation.

Example: You order tests for loci E, K and A for one dog - total price = 16.70 EUR + 33.30 EUR (locus E) + 33.30 EUR (locus K) + 33.30 EUR (locus A) = 116.60 EUR

If any other genetic examination is ordered in addition to the locus test, you will get a discount.

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References:

Schmutz SM, Berryere TG, Ellinwood NM, Kerns JA, Barsh GS (2003) MC1R studies in dogs with melanistic mask or brindle patterns. J Hered 94, 69-73