Allele e2 in Australian Cattle Dogs

The e2 allele is another allele of the E locus that impacts coat colour in dogs. The e2 allele causes a non-standard cream colour in Australian cattle dogs. The cause is the c.-432G>C mutation in the MC1R gene. The cream colour is carried by individuals with genotype e2/e2 and e1/e2.

.

Reference:

Dürig, N., Letko, A., Lepori, V., Hadji Rasouliha, S., Loechel, R., Kehl, A., Hytönen, M.K., Lohi, H., Mauri, N., Dietrich, J., Wiedmer, M., Drögemüller, M., Jagannathan, V., Schmutz, S.M., Leeb, T. : Two MC1R loss-of-function alleles in cream-coloured Australian Cattle Dogs and white Huskies. Anim Genet 49:284-290, 2018. Pubmed reference: 29932470 . DOI: 10.1111/age.12660.