Melanistic mask EM (black mask)

For an overview of dog coat color hierarchy continue to the article Introduction into coat color in dogs.

In connection with the melanistic mask, the allele E^Mhas been identified that was created by point-substitution c.790A

However, not all dogs with the E^M-allele have a melanistic mask. With dogs having brown, black or blue coat, it is often difficult to distinguish the melanistic mask from the coat colour.

Examples:

• Brindle greyhound with dilution gene (D-locus) - the light-grey brindling turns in fawn brindling - the melanistic mask may merge with the overall coat colour (the black mask turns grey or even white)
• Scottish Deerhound breed is usually grey-spotted and the melanistic mask may merge with the overall coat colour (the black mask turns grey or even white)

The colour of the melanistic mask corresponds with the other genes affecting the production of the eumelanin type and therefore, the melanistic mask may not be always black.

The E^M-locus test is suitable in particular for the following breeds: Afghan, Bull Mastif, Cairn Terrier, Cardigan Welsh Corgi, German Shepherd, Great Dane, Greyhound, Saluki, Staffordshire Bull Terrier, Whippet.

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References:

Schmutz SM, Berryere TG, Ellinwood NM, Kerns JA, Barsh GS (2003) MC1R studies in dogs with melanistic mask or brindle patterns. J Hered 94, 69-73