Testing of cats: VDDRI

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Usual turnaround time: 12 business days
1 test price: 56.00 $ without VAT

Vitamin D-deficiency rickets, type IA

Rickets is an autosomal recessive disorder. The disease affects cats with P/P (positive / positive) genotype only. Cats with P/N (positive /negative) genotype are clinically without any symptoms. They are genetically considered carriers of the disease (heterozygotes). In offspring of two heterozygous animals following genotype distribution can be expected: 25 % N/N (healthy non-carriers), 25 % P/P (affected), and 50 % N/P (healthy carriers). Because of high risk of producing affected offspring, mating of two N/P animals (carriers) can not be recommended.

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References:

Grahn, R.A., Ellis, M.R., Grahn, J.C., Lyons, L.A. : A novel CYP27B1 mutation causes a feline vitamin D-dependent rickets type IA. J Feline Med Surg 14:587-90, 2012. Pubmed reference: 22553308

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Usual turnaround time: 12 business days
1 test price: 56.00 $ without VAT