Testing of dogs: PRA-prcd

Usual turnaround time: 12 business days

1 test price: 56.00 $ without VAT

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Total 74 related tests Show all Hide related tests

6-test for Australian Labradoodle ALAEU members can apply 10% discount
CDPA / CDDY (IVDD) + PRA-prcd for Nova Scotia Duck Tolling Retriever, Coton de Tulear, American Cocker Spaniel and more
CEA + PRA-prcd test combination for dogs
CNM + PRA doubletest for Labrador Retrievers for better price
Cerebellar ataxia + PRA-prcd
Chondrodysplasia + PRA-prcd combinations of tests for Karel Bear Dogs
Combination American Cocker Spaniel DM (SOD1A) + Gallbladder mucoceles + Locus EH + PFK + PRA prcd
Combination American Eskimo Dog DM + PLL + PRA-prcd
Combination American Hairless Terrier PLL + PRA-prcd + vWDI + DM + hairless
Combination Australian Koolie CEA + Cystinuria II + DM (SOD1A) + MDR1 + PLL + PRA-prcd + TNS
Combination Australian Labradoodle CNM + DM* (SOD1A) + NEWS + PRA-prcd + PRA-rcd4 + Dwarfism (Skeletal dysplasia 2) + VWD type I + DMD
Combination Australian Silky Terrier PRA-prcd + PLL + vWD type I
Combination Australian Stumpy Tail Cattle Dog PRA-prcd + NCL5 + PLL + Short Tail
Combination Australian cattle dog Cystinuria II + DM (SOD1A) + MC + NCL5 + NCL12 + PLL + PRA-prcd + PRA-rcd4
Combination Australian shepherd 1 CEA + DM (SOD1A) + HC (HSF4) + Lokus B aus + MDR1 + NCL6 + PRA-prcd + Short Tail - Bob Tail + CMR1 + HUU
Combination Australian shepherd 2 CEA + DM (SOD1A) + HC (HSF4) + Lokus B aus + MDR1 + NCL6 + PRA-prcd + Short Tail - Bob Tail + CMR1 + HUU + PCD + Hyposegmentation of granulocytes + Myeloencephalopathy, progressive degenerative
Combination Barbet - French Water Dog HUU + PRA-prcd + vWD I + vWD II + locus D1 + locus KB
Combination Bearded Collie CEA + PRA-prcd + MDR1
Combination Boykin Spaniel CEA + DM (SOD1A) + PRA-prcd
Combination Chesapeake Bay Retriever CDPA / CDDY (IVDD) + DM (SOD1A) + PRA-prcd + c1 curly coat
Combination Chihuahua CDPA / CDDY (IVDD) + PRA-prcd + MTC + NCL7
Combination Chinese Crested Dog Hairlessness(FOXI3) + CMSD + DM (SOD1A) + PLL + PRAprcd + PRA-rcd3 + NCL7 + vWDII
Combination Chinese Crested Dog 2 CMSD + DM (SOD1A) + PLL + PRAprcd + PRA-rcd3 + NCL7 + vWDII
Combination Coton de Tuléar BNAt + CMR2 + DM (SOD1A) + HUU + IVDD + PHI + PRA-prcd + vWDI
Combination Curly Coated Retriever CORD1 + GSDIIIa + PRA-prcd
Combination English Cocker Spaniel AMS + BSS + DM (SOD1A) + FN + Gallbladder mucoceles + Locus EH + PFK + PRA-prcd + Xanthinuria II
Combination Finnish Hound Cerebellar ataxia + FVII + PRA-prcd
Combination Finnish Lapphund (Suomenlapinkoira) CMR3 + DM (SOD1A) + GSDII + HUU + PRA-prcd
Combination German Spitz PRA in German Spitz + PRA-prcd + VWD Type II
Combination Golden Retriever GRPRA-1 and 2 + Ichthyosis 1 and 2 + NCL5 + PRA-prcd + GRMD
Combination Golden Retriever XXL GRPRA-1 and 2 + Ichthyosis 1 and 2 + NCL5 + PRA-prcd + GRMD + vWDI + Epidermolysis bullosa + Osteogenesis imperfecta + DM + CMS in Golden Retrievers + Polyneuropathy + Hypomyelinating polyneuropathy
Combination Jack Russell Terrier DM (SOD1A) + LOA + PLL + PRA-prcd + SCA + SCID + JBD + CMS
Combination Japanese Chin GM2 + MH + PRA-prcd
Combination Karelian Bear Dog Chondrodysplasia + Short Tail + PRA-prcd + Hypophosphatasia
Combination Labrador Retriever CNM + DM(SOD1A) + PRA-prcd + PKdef + HUU + SD2 + STGD + MTC
Combination Labrador Retriever XXL Achromatopsia + Alexander disease + CMS + CNM + Cystinuria + DM (SOD1A) + Dwarfism (SD2) + DAMS + EIC + HNPK + HUU + LPPN3 + MH + MTC + MTM1 + MDL - Muscular dystrophy, Ullrich type + Muscular dystrophy-dystroglycanopathy + Narcolepsy + Obesity + OSD + PK deficiency + PRA-prcd + STGD
Combination Labrador Retriever for Retriever Klub CZ
Combination Lancashire Heeler CEA + DM (SOD1A) + PLL + PRA-prcd
Combination Lapponian Herder (Lapinporokoira) CEA + CMR3 + DM (SOD1A) + GSDII + PRA-prcd + PRA in Lapponian Herder
Combination Manchester terrier PLL + PRA-prcd + vWDI + Xanthinuria II in Manchester Terriers + DCM
Combination Miniature American Shepherd CEA + DM (SOD1A) + HC + MDR1 + NCL6 + PRA-prcd
Combination Norwegian Elkhound Grey Chondrodysplasia + POAG + PRA-prcd + Ataxia in Norwegian Elkhound
Combination Norwegian Elkhounds PRA-prcd + Ataxia in Norwegian Elkhound + POAG
Combination Nova Scotia Duck Tolling Retriever CEA + DM (SOD1A) + PRA-prcd + CDMC + CL/P
Combination Nova Scotia Duck Tolling Retriever XXL CEA + DM (SOD1A) + IVDD + PRA-prcd + CDMC + CL/P (CLPS) + CP1 + CLAM (DCM) + locus D
Combination Papillon and Phaléne DM (SOD1A) + FVII + NAD + papPRA1 + PRA-prcd + vWDI
Combination Parson Russell Terrier DM (SOD1A) + HUU + LOA + PLL + PRA-prcd + SCA + SCID + JBD + CMS
Combination Poodle NEWS + prcd-PRA + rcd4-PRA + DM(SOD1A) + vWD1 + GM2 + loci E and B
Combination Portuguese Warren Hound - portuguese Podengo CORD1 + DM (SOD1A) + PRA-prcd
Combination Portuguese Water Dog PRA-prcd + RSPO2 + GM1 + EOPRA
Combination Puli DM (SOD1A) + PLL + PRA-prcd + vWDI + BBS4 + Locus A + Locus E + Locus K, KB allele only
Combination Rat Terrier DM (SOD1A) + PLL + PRA-prcd + CHG in Rat Terriers and Toy Fox Terriers
Combination Romagna Water Dog (Lagotto romagnolo) HUU + JE + LSDs + PRA-prcd + RSPO2
Combination Russian Black Terrier HUU + JLPP + PLL + PRAprcd + DM* (SOD1A)
Combination Schipperke Short Tail + PRA-prcd + vWDI
Combination Schnauzer Giant DCM + DM (SOD1A) + FVII + HUU + PRA-prcd + PRA NECAP1
Combination Spanish Waterdog NAD + CHG + PRA-prcd + DM* (SOD1A) + EO-PRA + Short Tail + PRA-PDE6B
Combination Spanish Waterdog 2 NAD + CHG + PRA-prcd + DM* (SOD1A) + EO-PRA + Short Tail + PRA-PDE6B + RSPO2 + CDPA / CDDY (IVDD)
Combination Swedish Lapphund CMR3 + DM (SOD1A) + GSDII + PRA-prcd
Combination Tibetan Terrier DM (SOD1A) + Dwarfism + NCLTT + PLL + PRA-prcd + PRA-rcd4 + PRA3
Combination Toy Spitz (Pomeranian) Gallbladder mucoceles + PRA-rcd3 + PRA-prcd + Vitamin D-deficiency rickets
Combination Yorkshire Terrier DM + HUU + PLL + PRA-prcd
DM (SOD1A) + PRA-prcd Double test for Puli
FN + PRA FN + PRA for English Cocker Spaniels
HC + PRA test combination HC + PRA for Shepherds
MDR1 + PRA test combination for Shepherds
NAD + CHG + PRA-prcd for Spanish water dogs
NAD + PRA-prcd for Spanish water dogs
PLL + PRA for Chinese Crested dogs, Australian cattle dogs and some other breeds with PLL and PRA-prcd assumption
PRA-prcd + PRA-rcd3
PRA-prcd + PRA-rcd4 Double test for lower price!
PRA-prcd + RSPO2 + GM1 combination of tests for Portuguese water dogs
cord1-PRA + PRA-prcd
vWD I + PRA-prcd for Poodles, Labradoodles, Goldendoodles

PRA-prcd (progressive rod-cone degeneration)

The progressive rod-cone degeneration (PRA-prcd) is caused by mutation c.5G>A in PRCD gene (former designated as 1298G>A). The PRCD gene affects mainly retina with the same expression level in retinal pigment epithelium, photoreceptor cells and in the ganglion cells. The mutation causes exchange of nucleon TGC basis for TAC basis that results in binding of other amino acid and structural and functional changes in the resulting protein.

This genetic disorder causes that photosensitive cells of the retina (rods and cones) gradually deteriorate and die. The onset of the disease is in adolescence or in early adulthood. However, the age of the disease onset and the disease intensity depends on the specific breed. The rod-type cells lose their function first and the affected dogs will develop night blindness. Over time the disease continues with cone degeneration and progresses to complete blindness.

The genetic testing can help to clarify the diagnosis. It can determine the dog genotype and is the solution for gradual elimination of prcd occurrence in a breed. It is necessary to be aware that not all retinal diseases belong in progressive retina atrophy group of disorders and not all are a variant of PRA-prcd. In many breeds, the cause of PRA inheritance has not been still clarified. It is also possible that several mutations can be responsible for retinal atrophy in one breed. Therefore, we recommend that an eye examination by a veterinary ophthalmologist is performed every year.

The analysis is performed by partner laboratory.

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Breed list - total 74 different breeds. Show list of all breeds Hide breeds